Infection-related cerebral venous sinus thrombosis (CVST) is a rare cerebral vascular diseases which has no pathognomonic sign or definite diagnostic approach. It is crucial to early suspect and recognize the disease to lower morbidity and mortality of it. However, its low incidence and atypic presentation often leads to misdiagnosis and treatment delay which increase complications and mortality of septic CVST. The patient of this study is a 26-year-old man presented with complaint of agitation, ataxia, weakness and confusion three weeks after ABSCESS drainage. On examination, right abduscent nerve palsy, bilateral papilledema, left eye vision loss (hand motion at 1 meters), right hemiparesis, right central facial hemiparesis and fever (T: 38.4) were noted. Magnetic resonance imaging and venography was performed which showed CVST with left occipital lobe infarction. The patient received antibiotics and his symptoms and signs subsided gradually.

Introduction: Basal cell adenoma (BCA) is a rare benign epithelial tumour of the salivary gland majorly involving the parotid gland, and rarely the SUBMANDIBULAR gland. Case Report: We describe a rare case of BCA of the SUBMANDIBULAR gland diagnosed preoperatively using fine needle aspiration cytology in a 60-year-old woman presenting with painless SUBMANDIBULAR swelling. The surgery went uneventfully, and the histopathological examination confirmed the diagnosis. Conclusions: BCA can be accurately diagnosed only through histological observations due to its resemblance to various benign and malignant salivary and non-salivary gland tumours, which are difficult to biopsy.

Schwannoma of the hypoglossal nerve is an uncommon benign neoplasm. We present a 49-year-old female patient with hypoglossal schwannoma presenting as a painless mass in the SUBMANDIBULAR area.

Introduction: Mammary Analogue Secretory Carcinoma of salivary glands (MASC) is a low-grade carcinoma of salivary glands of the head-neck region. It bears histological resemblance to Secretory Carcinoma of the breast and Acinic Cell Carcinoma (ACC) of the parotid gland. Its clinical behaviour and aggressiveness vary amongst individuals and experience in MASC of the SUBMANDIBULAR gland are limited. Case Report: We report a 16-year-old female with binary neck swelling in the SUBMANDIBULAR region. The hard swelling in the SUBMANDIBULAR region was a MASC and the soft cystic mass was a synchronous congenital lymphatic cyst in the neck. We report two unusual features, an extremely rare involvement of MASC of SUBMANDIBULAR salivary gland and the presence of a congenital lymphatic cyst in the area adjacent to the main tumour mass. Treatment was done by surgical excision of both the neck masses intoto and ipsilateral selective neck dissection (Level I-IV). Conclusions: While MASC's histological pattern has been described in previous studies, its clinical picture is rarely documented. This report aims to shed light on the clinical presentation of this under-diagnosed entity and the aggressive management protocol required during preoperative workup, intraoperative disease clearance and post-operative follow up of such patients. MASC of the SUBMANDIBULAR salivary gland is an uncommon cause of neck swelling in the adolescent age group, but due to its occasional aggressive nature, should be borne in mind as a possible differential diagnosis of salivary gland tumours.

Introduction: SUBMANDIBULAR region is surgically significant in the head and neck field and a mass in this region may have multiple differential diagnoses. Case Report: An elderly man came with a single 4×2. 5 cm swelling in the neck on the right side, just below the lower jaw, since one month. Ultrasound showed an irregular heterogeneous hypoechoic lesion in the right SUBMANDIBULAR space measuring 37×23 mm with mild internal vascularity. The SUBMANDIBULAR gland appeared separate but compressed. Fine needle aspiration was suggestive of spindle cell neoplasm. The swelling was excised under general anesthesia. By histopathological examination, the lesion was diagnosed as anaplastic lymphoma kinase-negative inflammatory myofibroblastic tumor (IMT) based on focal immunoreactivity with cyclin D1. The patient then received radiotherapy 60 Gray divided into 30 fractions over 6 weeks. The case had no evidence of recurrence or residual disease six months post-surgery. Conclusion: Tumefactive spindle-cell lesion in the head and neck can comprise inflammatory conditions, benign and malignant neoplasms or borderline neoplasms, such as nodular fasciitis and IMT. The definitive histologic diagnosis of IMT helps in tailoring the treatment modality based on its locally aggressive biologic potential.

Background and Objectives: Brain ABSCESS remains a potentially fatal central nervous system (CNS) disease, especially in developing countries. Anaerobic ABSCESS is difficult to diagnose because of cumbersome procedures associated with the isolation of anaerobes.Materials and Methods: This is a hospital-based retrospective microbiological analysis of 430 brain ABSCESS materials (purulent aspirates and/or tissue), for anaerobic organisms, that were received between 1987-2014, by the Microbiology Laboratory in our Institute.Results: Culture showed growth of bacteria 116.430 (27%) of the cases of which anaerobes were isolated in 48.116 (41.1%) of the cases. Peptostreptococcus (51.4%), was the predominant organism isolated in four cases followed by Bacteroides and Peptococcus species.Conclusion: Early diagnosis and detection of these organisms would help in the appropriate management of these patients.